The morphological characteristic, anatomical  venom duct, structure of radular teeth, a.a sequence of toxin and three-dimensional structure of Conus tessulatus’s (vermivorous feeding mode) toxin protein in Nha Trang Bay, Khanh Hoa Province were studied. The results showed that venom buld of C. tessulatus has a sickle milky white shape, venom duct has pale yellow, radular sac has reddish, radular teeth of C. tessulatus are soft structure and small size, have serration, one bard. Results of α-conotoxin protein sequencing were used to construct deduced a.a sequence of the toxin protein from C. tessulatus. From this a.a sequence, framework of CC-C-C specific to α-conotoxin be determined and three dimensional of C. tessulatus’ s toxin protein structure be modeled to understand the functions of α-conotoxin from C. tessulatus based on homological proteins known in the database. This study provides a protein database for applications in the production of drugs used in the treatment for neurological diseases